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beta Amyloid 1-16 抗体

适用: 人, 小鼠 WB, IF, IP, IHC, ELISA 宿主: 小鼠 Monoclonal Ab3 unconjugated
产品编号 ABIN2961825
发货至: 中国
  • 抗原
    beta Amyloid 1-16
    适用
    人, 小鼠
    宿主
    • 2
    小鼠
    克隆类型
    • 1
    • 1
    单克隆
    标记
    • 2
    非结合性
    应用范围
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA
    特异性
    Reacts with humanand mouse Aβ1-16 as well as other Aβ peptides: Aβ37, Aβ38, Aβ39, Aβ40 and Aβ42
    纯化方法
    Purified
    免疫原
    Synthetic peptide corresponding to Abeta1-16.
    克隆位点
    Ab3
    亚型
    IgG1
  • 应用备注
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    1 - 10 μg/mL for any applications
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.4.
    注意事项
    Dilute in PBS or medium which is identical to that used in the assay system.
    储存条件
    -20 °C
    储存方法
    Stable for at least one year at -20°C
    有效期
    12 months
  • 抗原
    beta Amyloid 1-16
    别名
    Amyloid beta 1-16
    背景
    Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Aβ is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Aβ. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the 8-16 amino acidic region of Aβ (1-16).

    Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Gene name: APP, A4, AD1
    基因ID
    351
    UniProt
    P05067
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