beta Amyloid 1-16 抗体
This 小鼠 单克隆 antibody specifically detects beta Amyloid 1-16 in WB, IF, IP, IHC 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN2961825
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for beta Amyloid 1-16 抗体 (ABIN2961825)
抗原
beta Amyloid 1-16
适用
人, 小鼠
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA
克隆位点
Ab3
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特异性
- Reacts with humanand mouse Aβ1-16 as well as other Aβ peptides: Aβ37, Aβ38, Aβ39, Aβ40 and Aβ42
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纯化方法
- Purified
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免疫原
- Synthetic peptide corresponding to Abeta1-16.
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亚型
- IgG1
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anti-beta Amyloid 1-16 (AA 1-16) antibody
适用: 人 WB, IF (p), IHC (p) 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL for any applications -
限制
- 仅限研究用
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缓冲液
- PBS, pH 7.4.
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注意事项
- Dilute in PBS or medium which is identical to that used in the assay system.
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储存条件
- -20 °C
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储存方法
- Stable for at least one year at -20°C
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有效期
- 12 months
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- beta Amyloid 1-16
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别名
- Amyloid beta 1-16
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背景
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Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Aβ is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Aβ. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the 8-16 amino acidic region of Aβ (1-16).
Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Gene name: APP, A4, AD1 -
基因ID
- 351
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UniProt
- P05067
抗原
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