TNNI3 抗体
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北京 101111
Quick Overview for TNNI3 抗体 (ABIN295183)
抗原
See all TNNI3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human cardiac-specific troponin I, (TnI) an integral inhibitory protein of cardiac muscle which exists as a complex with troponin C (TnC) and troponin T (TnT). The TnT subunit of troponin binds to tropomyosin to form a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, enabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurement of blood TnI and TnT levels is an important diagnostic indicator of heart muscle damage, and can be used to differentiate between angina and myocardic infarction in patients with chest pain. Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro.
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纯化方法
- Affinity purified
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免疫原
- Native human cardiac troponin I, purity greater than 98%.
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亚型
- IgG
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anti-Cardiac Troponin I (TNNI3) (AA 102-210) antibody
TNNI3 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 2-211) antibodyTNNI3 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 1-211) antibodyTNNI3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) antibodyTNNI3 适用: 人, 犬, 猴 WB, IF 宿主: 小鼠 Monoclonal 4E5 unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 1-211) antibodyTNNI3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 117-127) antibodyVerified TNNI3 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (pSer44) antibodyTNNI3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) antibodyTNNI3 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 2I-14 unconjugated
anti-Cardiac Troponin I (TNNI3) antibodyTNNI3 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 8I-7 unconjugated
anti-Cardiac Troponin I (TNNI3) antibodyTNNI3 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 8I-7 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- TNNI3 (Cardiac Troponin I (TNNI3))
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别名
- TNNI3 / CTnI
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背景
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Name/Gene ID: TNNI3
Synonyms: TNNI3, CTnI, CMD1FF, CMD2A, RCM1, Troponin I, cardiac, Troponin I, cardiac muscle, Troponin I type 3 (cardiac), Cardiac troponin I, CMH7 -
基因ID
- 7137
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UniProt
- P19429
抗原
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