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IL-17 抗体

This 兔 多克隆 antibody specifically detects IL-17 in WB, ELISA 和 Func. It exhibits reactivity toward 人.
产品编号 ABIN293413
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-17 抗体 (ABIN293413)

抗原

See all IL-17 (IL17) 抗体
IL-17 (IL17) (Interleukin 17 (IL17))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-17 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Functional Studies (Func)
  • 特异性

    Recognizes human IL-17 (Interleukin-17/17A), a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.

    纯化方法

    Purified

    免疫原

    Recombinant human IL-17.

    Type of Immunogen: Recombinant protein

    亚型

    IgG
  • 应用备注

    Approved: ELISA (0.5 - 2 μg/mL), Func (0.93 - 1.3 μg/mL), WB (0.1 - 0.2 μg/mL)

    Usage: ELISA: May be used in an indirect ELISA or as the capture reagent in a sandwich ELISA. Western Blot: May be used under either reducing or non-reducing conditions.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.

    浓度

    Lot specific

    缓冲液

    Lyophilized, PBS,  pH 7.4.
  • 抗原

    IL-17 (IL17) (Interleukin 17 (IL17))

    别名

    IL17

    背景

    Name/Gene ID: IL17

    Synonyms: IL17
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