IL-17 抗体
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北京 101111
Quick Overview for IL-17 抗体 (ABIN293413)
抗原
See all IL-17 (IL17) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human IL-17 (Interleukin-17/17A), a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
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纯化方法
- Purified
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免疫原
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Recombinant human IL-17.
Type of Immunogen: Recombinant protein -
亚型
- IgG
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应用备注
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Approved: ELISA (0.5 - 2 μg/mL), Func (0.93 - 1.3 μg/mL), WB (0.1 - 0.2 μg/mL)
Usage: ELISA: May be used in an indirect ELISA or as the capture reagent in a sandwich ELISA. Western Blot: May be used under either reducing or non-reducing conditions. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.
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浓度
- Lot specific
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缓冲液
- Lyophilized, PBS, pH 7.4.
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- IL-17 (IL17) (Interleukin 17 (IL17))
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别名
- IL17
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背景
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Name/Gene ID: IL17
Synonyms: IL17
抗原
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