Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA
交叉反应 (详细)
ThIS Rat UCP4 peptide sequence is 100 % conserved in alternatively spliced isoforms a-c of rat, 85 % in human, and 71 % in mouse UCP4. UCP42-P has no significant homology with UCP1-3 or UCP-5.
纯化方法
Affinity chromatography purified
免疫原
UCP4 antibody was raised in rabbit using a 14 amino acid peptide from rat UCP4 as the immunogen.
Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. UCP3 is predicted to contain 6 transmembrane domains. UCP4 (mouse/rat 322 aa, human 323 aa, chromosome 6p11.2-q12) is expressed in both fetal and adult brain tissues.