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Oncostatin M 抗体

This anti-Oncostatin M antibody is a 兔 多克隆 antibody detecting Oncostatin M in WB, ELISA 和 Inhibition. Suitable for 人.
产品编号 ABIN289518
发货至: 中国

Quick Overview for Oncostatin M 抗体 (ABIN289518)

抗原

See all Oncostatin M (OSM) 抗体
Oncostatin M (OSM)

适用

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宿主

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克隆类型

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多克隆

标记

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This Oncostatin M antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
  • 纯化方法

    Purified

    免疫原

    Oncostatin M antibody was raised in rabbit using highly pure recombinant human oncostatin M as the immunogen.
  • 应用备注

    ELISA: 0.5-2 µg/mL, Inhibition: 0.1-0.175 µg/mL, WB: 0.1-0.2 µg/mL
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in sterile water to a concentration of > 0.2 mg/mL.

    浓度

    Lot specific

    缓冲液

    Lyophilized from 0.5 x PBS, pH 7.4.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原

    Oncostatin M (OSM)

    别名

    Oncostatin M

    背景

    Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activate T cells, monocytes and Kaposi’s sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi’s sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL6, and CNTF. Human OSM is active on Mouse cells.

    分子量

    23.9 kDa (predicted detection band MW)

    途径

    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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