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IL-4 抗体

This anti-IL-4 antibody is a 兔 多克隆 antibody detecting IL-4 in WB, ELISA 和 Inhibition. Suitable for 小鼠.
产品编号 ABIN289356
发货至: 中国

Quick Overview for IL-4 抗体 (ABIN289356)

抗原

See all IL-4 (IL4) 抗体
IL-4 (IL4) (Interleukin 4 (IL4))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This IL-4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
  • 纯化方法

    Purified

    免疫原

    IL4 antibody was raised in rabbit using highly pure recombinant murine IL-4 as the immunogen.
  • 应用备注

    ELISA: 0.5-2 µg/mL, Inhibition: 0.78-1.16 µg/mL, WB: 0.1-0.2 µg/mL
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in sterile water to a concentration > 0.2 mg/mL.

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS, pH 7.4.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原

    IL-4 (IL4) (Interleukin 4 (IL4))

    别名

    IL4

    背景

    IL4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL4, IL5, IL6, IL10, and IL13, which favor a humoral immune response. Another dominant function of IL4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL4 production by Th2 cells has been associated with elevated IgE production and allergy.

    分子量

    14 kDa (predicted detection band MW)

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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