Resistin 抗体 (Biotin)
Quick Overview for Resistin 抗体 (Biotin) (ABIN288463)
抗原
See all Resistin (RETN) 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- Resistin antibody (biotin) was raised in goat using highly pure recombinant human resistinas the immunogen.
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应用备注
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ELISA: 0.25-1 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in sterile PBS with 0.1 % BSA to a concentration of at least 50 µg/mL
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.2.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Resistin (RETN)
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别名
- Resistin
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背景
- Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis.
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分子量
- 20.2 kDa (predicted detection band MW)
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途径
- Feeding Behaviour, Smooth Muscle Cell Migration
抗原
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