HYOU1 抗体 (Atto 488)
Quick Overview for HYOU1 抗体 (Atto 488) (ABIN2868630)
抗原
See all HYOU1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Detects ~170 kDa.
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Protein G Purified
-
免疫原
- Recombinant Full length GRP170 Protein
-
亚型
- IgG2b
-
-
anti-Hypoxia Up Regulated 1 (HYOU1) (C-Term) antibody
HYOU1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 901-999) antibodyHYOU1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6F7 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 401-500) antibodyHYOU1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 695-994) antibodyHYOU1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (PerCP)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 PerCP
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (APC)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 APC
anti-Hypoxia Up Regulated 1 (HYOU1) antibodyHYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (HRP)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 HRP
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (FITC)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 FITC
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (Biotin)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 Biotin
-
-
应用备注
-
- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
-
说明
-
1 μg/ml of ABIN2868630 was sufficient for detection of GRP170 in 20 μg of HEK293 lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Conjugated antibodies should be stored at 4°C
-
-
- HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
-
别名
- GRP170
-
背景
- GRP170, also known as ORP150, is the largest member of glucose-regulated Antibodys, and acts as a human chaperone Antibody. It is thought to play an important role in Antibody folding and secretion in the ER. Suppression of the Antibody is associated with accelerated apoptosis, therefore having an important cryoprotective role in hypoxia-induced cellular pertubation. This cryopotective role has led to an anti-tumor immune response, which will hopefully lead to therapeutic immunizations against cancers (1). GRP170 has also been shown to bind with dendritic cells and provide the danger signals to induce anti-tumor immune responses (2).
-
基因ID
- 10525
-
NCBI登录号
- NP_006389
-
UniProt
- Q9Y4L1
-
途径
- ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
抗原
-
