SNCAIP 抗体
Our Local Distributor
北京 101111
Quick Overview for SNCAIP 抗体 (ABIN285957)
抗原
See all SNCAIP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
免疫原
- Synphilin 1 antibody was raised in goat using a peptide, SLELNGEKDKDKGRTLQRT, as the immunogen.
-
-
-
-
应用备注
-
ELISA: >1:10,655, IHC-P: >1:400, WB: >1:2,000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Supplied as liquid whole serum without preservative
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
-
-
- SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
-
别名
- Synphilin 1
-
背景
- Synphilin-1 is a cytoplasmic protein that is enriched in the neurophil of normal human brain. Although the exact function of synphilin-1 is unknown, it may possibly have a role as a cytoskeletal protein based on the presence of ankyrin-like repeats and an ATP, GTP-binding domain. It has been shown to be novel is its ability to associate in vivo with a-synuclein to form cytoplasmic eosinophilic inclusions. Additionally, it has been observed to be present in Lewy bodies of Parkinson disease, which are composed of a-synuclein. Because synphilin-1 is not found in protein aggregates of Alzheimer’s disease, it appears to be specific for a-synuclein-containing lesions. Synphilin-1 may facilitate the aggregation of a-synuclein into Lewy bodies.
抗原
-