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SNCAIP 抗体

SNCAIP 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN285957
发货至: 中国
  • 抗原 See all SNCAIP 抗体
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    适用
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    宿主
    • 31
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    山羊
    克隆类型
    • 33
    • 1
    多克隆
    标记
    • 16
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    • 2
    • 1
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    • 1
    • 1
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    This SNCAIP antibody is un-conjugated
    应用范围
    • 28
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    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    免疫原
    Synphilin 1 antibody was raised in goat using a peptide, SLELNGEKDKDKGRTLQRT, as the immunogen.
    Top Product
    Discover our top product SNCAIP Primary Antibody
  • 应用备注
    ELISA: >1:10,655, IHC-P: >1:400, WB: >1:2,000
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Supplied as liquid whole serum without preservative
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • 抗原
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    别名
    Synphilin 1 (SNCAIP 产品)
    背景
    Synphilin-1 is a cytoplasmic protein that is enriched in the neurophil of normal human brain. Although the exact function of synphilin-1 is unknown, it may possibly have a role as a cytoskeletal protein based on the presence of ankyrin-like repeats and an ATP, GTP-binding domain. It has been shown to be novel is its ability to associate in vivo with a-synuclein to form cytoplasmic eosinophilic inclusions. Additionally, it has been observed to be present in Lewy bodies of Parkinson disease, which are composed of a-synuclein. Because synphilin-1 is not found in protein aggregates of Alzheimer’s disease, it appears to be specific for a-synuclein-containing lesions. Synphilin-1 may facilitate the aggregation of a-synuclein into Lewy bodies.
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