Botulinum Neurotoxin Type A 抗体
Quick Overview for Botulinum Neurotoxin Type A 抗体 (ABIN2859514)
抗原
适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Protein G Sepharose Chromatography.
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免疫原
- Type A Neurotoxin and Complexing Proteins Toxoid.
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应用备注
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Suitable for use in Dot blot, ELISA (1/10,000) and Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.5 mg/mL (OD280nm, E0.1%=1.4)
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缓冲液
- 1x PBS, pH 7.2 containing 20 % Glycerol and no preservative.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- Botulinum Neurotoxin Type A
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背景
- Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.Synonyms: BOTOX, BoNT/A, Bontoxilysin-A, Clostridium botulinum Toxin A
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基因ID
- 1491
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UniProt
- P10845
抗原
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