Rotavirus (RV) 抗体
This 小鼠 单克隆 antibody specifically detects Rotavirus in WB 和 EIA. It exhibits reactivity toward Rotavirus.
产品编号 ABIN2859489
发货至:
中国
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Quick Overview for Rotavirus (RV) 抗体 (ABIN2859489)
抗原
Rotavirus (RV)
适用
Rotavirus
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
克隆位点
521
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纯化方法
- Protein A chromatography.
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免疫原
- Strain MR bovine rotavirus
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亚型
- IgG2
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anti-Rotavirus (RV) antibody
RV 适用: Rotavirus ELISA, IF, WB, IHC, IP 宿主: 小鼠 Monoclonal Rota-VP6 unconjugated
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应用备注
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Suitable for use in ELISA and Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL (OD280 nm, E0.1% = 1.3)
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缓冲液
- 0.01 M PBS, pH 7.2 containing 0.09 % sodium azide as preservative and no stabilizers.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Rotavirus (RV)
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别名
- Rotavirus
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物质类
- Virus
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背景
- Rotaviruses, members of the family Reoviridae, are a major cause of diarrhoea in young mammals. Rotavirus infections also result in economic losses in agriculture due to diarrhoea in calf, pig, sheep, and poultry rearing. Diarrhoea (or scours) due to the rotavirus Nebraska Calf Diarrhea Virus can affect calves up to 30 days of age or older. Diarrhoea begins 2 to 3 days after exposure. Diagnosis is by history, lesions (ulcers on the tongue, lips, and mouth) and diagnostic laboratory tests. Mortality rates may be as high as 50 percent, depending on the secondary bacteria present. Human rotaviruses, the major aetiological agents of severe infantile diarrhoea worldwide, display surprisingly diverse and complex serotypic specificities. Rotaviruses are 70 nm, non enveloped viruses comprised of a triple layered protein capsid, Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection, therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.
抗原
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