PDGFRB 抗体 (AA 1013-1025)
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北京 101111
Quick Overview for PDGFRB 抗体 (AA 1013-1025) (ABIN285907)
抗原
See all PDGFRB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1013-1025
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交叉反应
- 小鼠
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纯化方法
- Protein G affinity chromatography
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免疫原
- PDGF receptor beta antibody was raised in rabbit using a synthetic peptide (QPNEGDNDYIIPLA) corresponding to amino acids 1013-1025 of human PDGF receptor beta as the immunogen.
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亚型
- IgG
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应用备注
- Optimal conditions should be determined byt he investigator.
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限制
- 仅限研究用
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状态
- Frozen
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浓度
- Lot specific
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缓冲液
- Frozen in 0.1 M tris-glycine buffer, pH 7.4, with 0.11 NaCl, and 0.05 % NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C.
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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别名
- PDGF Receptor beta
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背景
- Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.
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分子量
- 190 kDa (predicted detection band MW)
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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