This AB is 100 % conserved in Mouse and Rat, 91% in Golden hamster, 83% in Rabbit and Pig, and 75% in Human and Canine.
交叉反应 (详细)
This rat D3R peptide sequence is 88 % conserved in mouse and 63 % with human/monkey D3R receptors (1-2). No significant sequence homology with other dopamine receptors (D1, D2, D4 or D5).
免疫原
Dopamine D3 receptor antibody was raised in rabbit using a 19 amino acid peptide of human D3 R as the immunogen.
ELISA: 0.5-1 µg/mL, IHC: 2-10 µg/mL, WB: 1-10 µg/mL Optimal conditions should be determined by the investigator.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in PBS at 1 mg/mL.
浓度
Lot specific
缓冲液
Lyophilized from PBS, with 0.1 % BSA, and 0.05 % NaN3.
储存液
Sodium azide
注意事项
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
抗原
DRD3
(Dopamine Receptor D3 (DRD3))
别名
Dopamine D3 Receptor
背景
Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. D3 is encoded by the Dopamine receptor D3 gene (DRD3). Maximum expression of dopamine D3 receptors is noted in the islands of Calleja and nucleus accumbens.