ADRA1B 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for ADRA1B 抗体 (C-Term) (ABIN2857085)
抗原
See all ADRA1B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
交叉反应
- 小鼠
-
产品特性
-
Rabbit polyclonal antibody to alpha 1b Adrenergic Receptor (adrenergic, alpha-1B-, receptor)
alpha 1b Adrenergic Receptor antibody -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha 1b Adrenergic Receptor. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.34 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))
-
别名
- adrenoceptor alpha 1B
-
背景
-
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Cellular Localization: Cell membrane -
分子量
- 57 kDa
-
基因ID
- 147
-
UniProt
- P35368
-
途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
-