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AFT1 抗体 (C-Term)

AFT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2857045
发货至: 中国
  • 抗原 See all AFT1 抗体
    AFT1 (Activating Transcription Factor 1 (AFT1))
    抗原表位
    • 28
    • 14
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 110
    • 46
    • 25
    • 9
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    宿主
    • 103
    • 7
    • 2
    • 1
    克隆类型
    • 99
    • 14
    多克隆
    标记
    • 60
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AFT1 antibody is un-conjugated
    应用范围
    • 81
    • 37
    • 22
    • 15
    • 15
    • 14
    • 14
    • 11
    • 11
    • 8
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to ATF1 (activating transcription factor 1)
    ATF1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATF1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product AFT1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HeLa

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    AFT1 (Activating Transcription Factor 1 (AFT1))
    别名
    activating transcription factor 1 (AFT1 产品)
    别名
    ews-atf1 antibody, fus/atf-1 antibody, treb36 antibody, ATF1 antibody, EWS-ATF1 antibody, FUS/ATF-1 antibody, TREB36 antibody, Atf-1 antibody, wu:fc92c07 antibody, zgc:64099 antibody, activating transcription factor 1 antibody, activating transcription factor 1 L homeolog antibody, atf1 antibody, ATF1 antibody, MGC85066 antibody, atf1.L antibody, Atf1 antibody
    背景
    This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.

    Cellular Localization: Nucleus
    分子量
    29 kDa
    基因ID
    466
    UniProt
    P18846
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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