PDE1A 抗体
This anti-PDE1A antibody is a 兔 多克隆 antibody detecting PDE1A in IHC (p) 和 WB. Suitable for 人.
Quick Overview for PDE1A 抗体 (ABIN2856821)
抗原
PDE1A
(Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1A (PDE1A))
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to PDE1A (calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A)
PDE1A antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human PDE1A. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: H1299 , HeLa , mouse brain , rat brain
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.74 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PDE1A (Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1A (PDE1A))
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别名
- phosphodiesterase 1A
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背景
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Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1, MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109], Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM]
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分子量
- 61 kDa
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基因ID
- 5136
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UniProt
- P54750
抗原
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