UNC13B 抗体 (Internal Region)
Quick Overview for UNC13B 抗体 (Internal Region) (ABIN2856793)
抗原
See all UNC13B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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交叉反应
- 小鼠, 大鼠, 牛
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交叉反应 （详细）
- Mouse (99 %), Rat (98 %), Bovine (99 %)
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产品特性
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Rabbit Polyclonal antibody to UNC13B (unc-13 homolog B (C. elegans))
UNC13B antibody [N3C1], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human UNC13B. The exact sequence is proprietary.
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亚型
- IgG
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anti-Unc-13 Homolog B (UNC13B) (AA 12-215) antibody
UNC13B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) (AA 1-350) antibodyUNC13B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) antibodyUNC13B 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) (AA 1062-1091) antibodyUNC13B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22476 unconjugated
anti-Unc-13 Homolog B (UNC13B) antibodyUNC13B 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) (AA 1482-1591) antibodyUNC13B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) (Internal Region) antibodyVerified UNC13B 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog B (UNC13B) antibodyUNC13B 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: 293T , H1299 , HeLa , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- UNC13B (Unc-13 Homolog B (UNC13B))
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别名
- UNC13B
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背景
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This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
Cellular Localization: Cytoplasm (By similarity) , Membrane, Peripheral membrane protein (By similarity) , Cell membrane (By similarity) , Cell junction , synapse (By similarity) -
分子量
- 181 kDa
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基因ID
- 10497
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途径
- Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
抗原
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