MAPKSP1 抗体
Quick Overview for MAPKSP1 抗体 (ABIN2856785)
抗原
See all MAPKSP1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to MP1 (MAPK scaffold protein 1)
MP1 antibody [N1C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Full length human MP1 Recombinant protein.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , Rat2 , Neuro2A , Raw264.7 , C2C12
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.88 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
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别名
- late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
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背景
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This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein.
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分子量
- 14 kDa
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基因ID
- 8649
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UniProt
- Q9UHA4
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途径
- PI3K-Akt Signaling
抗原
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