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FBXL3 抗体

This anti-FBXL3 antibody is a 兔 多克隆 antibody detecting FBXL3 in WB, ICC 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2856775
发货至: 中国

Quick Overview for FBXL3 抗体 (ABIN2856775)

抗原

See all FBXL3 抗体
FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

适用

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宿主

  • 40
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克隆类型

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多克隆

标记

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This FBXL3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to FBXL3 (F-box and leucine-rich repeat protein 3)
    FBXL3 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human FBXL3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: C2C12 , Molt-4

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.41 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Xu, Zhou, Yang, Chen, Li, Zhao, Liu, Li, Tan, Xiong, Sun: "The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor." in: Nature communications, Vol. 8, pp. 14002, (2018) (PubMed).

  • 抗原

    FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

    别名

    F-box and leucine rich repeat protein 3

    背景

    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.

    Cellular Localization: Nucleus , Cytoplasm

    分子量

    49 kDa

    基因ID

    26224

    UniProt

    Q9UKT7

    途径

    Photoperiodism
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