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CS 抗体

This anti-CS antibody is a 兔 多克隆 antibody detecting CS in WB, IP, ICC, IF, IHC (p) 和 IHC (wm). Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN2856769
发货至: 中国

Quick Overview for CS 抗体 (ABIN2856769)

抗原

See all CS 抗体
CS (Citrate Synthase (CS))

适用

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宿主

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克隆类型

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多克隆

标记

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This CS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Whole Mount) (IHC (wm))

质量等级

KO Validated
  • 交叉反应

    小鸡, Frog, 人, 猴, 小鼠, 大鼠, 斑马鱼

    产品特性

    Rabbit Polyclonal antibody to Citrate synthetase (citrate synthase)
    Citrate synthetase antibody [N2C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Citrate synthetase. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: mouse brain , rat brain , Rat muscle , 293T

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.65 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Ding, Rose, Sun, Wu, Chen, Lin, Yang, Chen, Lee, Xu, Tian, Akinwuntan, Zhao, Guan, Zhou, Chi: "MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis." in: Nature metabolism, Vol. 2, Issue 3, pp. 270-277, (2020) (PubMed).

    Leandro, Violante, Argmann, Hagen, Dodatko, Bender, Zhang, Williams, Bachmann, Auwerx, Yu, Houten: "Mild inborn errors of metabolism in commonly used inbred mouse strains." in: Molecular genetics and metabolism, Vol. 126, Issue 4, pp. 388-396, (2019) (PubMed).

    Kim, Men, Liang, Receno, Brutsaert, Korol, Heffernan, DeRuisseau: "Effects of long-term exposures to low iron and branched-chain amino acid containing diets on aging skeletal muscle of Fisher 344 × Brown Norway rats." in: Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme, Vol. 43, Issue 2, pp. 165-173, (2018) (PubMed).

    Nam, Akie, Sanosaka, Craige, Kant, Keaney, Cooper: "Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression." in: Scientific reports, Vol. 7, Issue 1, pp. 2013, (2018) (PubMed).

    Chang, Ulrich, Suliman, Piantadosi: "Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis." in: Free radical biology & medicine, Vol. 78, pp. 179-89, (2015) (PubMed).

  • 抗原

    CS (Citrate Synthase (CS))

    别名

    citrate synthase

    背景

    The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found.

    Cellular Localization: Mitochondrion matrix

    分子量

    52 kDa

    基因ID

    1431

    UniProt

    O75390
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