PCMT1 抗体
Quick Overview for PCMT1 抗体 (ABIN2856765)
抗原
See all PCMT1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase)
PCMT1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human PCMT1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 117-225) antibody
PCMT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 117-228) antibodyPCMT1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 62-286) antibodyPCMT1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 1-228) antibodyPCMT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G9 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (Internal Region) antibodyPCMT1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 165-227) antibodyPCMT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 18-55) antibodyPCMT1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB56325 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 93-126) antibodyPCMT1 适用: 人 WB 宿主: 兔 Polyclonal RB56324 unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 209-258) antibodyPCMT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) (AA 2-227) antibodyPCMT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.96 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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别名
- protein-L-isoaspartate (D-aspartate) O-methyltransferase
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背景
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Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.[supplied by OMIM]
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分子量
- 25 kDa
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基因ID
- 5110
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UniProt
- P22061
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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