F13A1 抗体 (N-Term)
Quick Overview for F13A1 抗体 (N-Term) (ABIN2856753)
抗原
See all F13A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit polyclonal antibody to Factor XIIIa (coagulation factor XIII, A1 polypeptide)
Factor XIIIa antibody [N1N3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human Factor XIIIa. The exact sequence is proprietary.
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亚型
- IgG
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anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 107-345) antibody
F13A1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 372-616) antibodyF13A1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 140-377) antibodyF13A1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) antibodyF13A1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) antibodyF13A1 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 9E2 unconjugated
anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 46-181) antibodyF13A1 适用: 人 WB, ELISA, IHC, IF, FACS, Coat, StM 宿主: 小鼠 Monoclonal F13A1-1448 unconjugated
anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 60-94) antibodyF13A1 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB57788 unconjugated
anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 380-520) antibodyF13A1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 170-204) antibodyF13A1 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB57789 unconjugated
anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 1-732) antibodyF13A1 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal M1 unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.97 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))
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别名
- coagulation factor XIII A chain
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背景
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This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits, and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.
Cellular Localization: Cytoplasm , Secreted -
分子量
- 83 kDa
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基因ID
- 2162
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UniProt
- P00488
抗原
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