Peptide sequence is <50 % identical to other mouse chemokine receptors inthis region and crossreacts with human CCR7
免疫原
CCR7 antibody was raised in goat using a synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acid residues 2-22 of mouse CCR7 as the immunogen.
ELISA: 1:100,000, FC: 1:10, IC: 1:250, IHC: 1:250, WB: 1:1,000 Optimal conditions should be determined by the investigator.
限制
仅限研究用
浓度
Lot specific
缓冲液
10 mM KHPO4, pH 7.2, with 140 M NaCl, 1 mg/mL BSA and 0.1 % NaN3.
储存液
Sodium azide
注意事项
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
储存条件
-20 °C/-80 °C
储存方法
Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.
抗原
CCR7
(Chemokine (C-C Motif) Receptor 7 (CCR7))
别名
CCR7
背景
C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. CCR7 has also recently been designated CD197 (cluster of differentiation 197). The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes.