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OFD1 抗体 (Center)

Cited in 1 publication. This 兔 多克隆 anti-OFD1 antibody specifically detects OFD1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN2856726
发货至: 中国
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Quick Overview for OFD1 抗体 (Center) (ABIN2856726)

抗原

See all OFD1 抗体
OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

适用

  • 15
  • 5
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宿主

  • 15

克隆类型

  • 15
多克隆

标记

  • 11
  • 2
  • 1
  • 1
This OFD1 antibody is un-conjugated

应用范围

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  • 7
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 2
    • 1
    • 1
    • 1
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    • 1
    Center

    产品特性

    Rabbit Polyclonal antibody to OFD1 (oral-facial-digital syndrome 1)
    OFD1 antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human OFD1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*

    说明

    Positive Control: Molt-4

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.96 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Zhang, Li, Siu, Luo, Yu: "Distinct Roles of TRAPPC8 and TRAPPC12 in Ciliogenesis via Their Interactions With OFD1." in: Frontiers in cell and developmental biology, Vol. 8, pp. 148, (2020) (PubMed).

  • 抗原

    OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

    别名

    OFD1

    背景

    This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified, a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. Alternatively spliced transcripts have been described for this gene but the biological validity of these transcripts has not been determined.

    Cellular Localization: Cytoplasm , Centrosome

    分子量

    117 kDa

    基因ID

    8481

    途径

    M Phase
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