PSMC3 抗体
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北京 101111
Quick Overview for PSMC3 抗体 (ABIN2856692)
抗原
See all PSMC3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 斑马鱼
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产品特性
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Rabbit polyclonal antibody to PSMC3 (proteasome (prosome, macropain) 26S subunit, ATPase, 3)
PSMC3 antibody [N1C2] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human PSMC3. The exact sequence is proprietary.
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亚型
- IgG
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anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) (AA 1-180) antibody
PSMC3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) antibodyPSMC3 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) (AA 53-152) antibodyPSMC3 适用: 人, 大鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1G10C9 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) (AA 1-180) antibodyPSMC3 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) (AA 1-300), (Regulatory Subunit) antibodyPSMC3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) antibodyPSMC3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) (AA 2-439) antibodyPSMC3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) (AA 1-439) antibodyPSMC3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) (AA 293-339) antibodyPSMC3 适用: 人, 小鼠, 大鼠, 非洲爪蟾, 犬, Cow, 兔, 马, 豚鼠, 猴, 小鸡, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) (Middle Region) antibodyPSMC3 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Molt-4
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))
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别名
- proteasome 26S subunit, ATPase 3
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背景
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.
Cellular Localization: Cytoplasm (Potential) , Nucleus -
分子量
- 49 kDa
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基因ID
- 5702
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UniProt
- P17980
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
抗原
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