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Liver Arginase 抗体

Name: Liver Arginase 抗体
Brand: antibodies-online
SKU: ABIN2856661
Availability: OutOfStock

This anti-Liver Arginase antibody is a 兔多克隆 antibody detecting Liver Arginase in WB, ELISA, FACS, IHC (p), IF, IP, ICC 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 11+ publications.

WB Image Sample (20 ug of whole cell lysate) A: mouse liver 10% SDS PAGE antibody diluted at 1:50000 (Liver Arginase 抗体)

ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using arginase I , antibody at 1:200 dilution. (Liver Arginase 抗体)

IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using arginase I , antibody at 1:500 dilution. (Liver Arginase 抗体)

IHC

WB Image Arginase 1 antibody detects Arginase 1 protein by western blot analysis. (Liver Arginase 抗体)

Elevated right ventricular pressure, increased right ventricular weight and altered expression of Ddah1 and Arg1 in cavin-/- mice. (Liver Arginase 抗体)

Elevated arginase1 expression and increased arginase inhibitor-induced relaxation of Cavin-1-/- arteries. (Liver Arginase 抗体)

Arg-1 expression in neutrophils and lymph-node microenvironmentNeutrophils isolated from control and HL patients were analysed for Arg-1 expression (A), activity by measuring urea (B) and protein expression by Western Blot (C). (Liver Arginase 抗体)

8 images

(11 references)

产品编号 ABIN2856661

发货至: 中国

Quick Overview for Liver Arginase 抗体 (ABIN2856661)

抗原

See all Liver Arginase (ARG1) 抗体

Liver Arginase (ARG1) (Arginase, Liver (ARG1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This Liver Arginase antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

质量等级

KO Validated

交叉反应

人, 小鼠, 大鼠

产品特性

Rabbit Polyclonal antibody to Arginase 1 (arginase, liver)
Arginase 1 antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Full length human Arginase 1 Recombinant protein.

亚型

IgG
anti-Arginase, Liver (ARG1) (C-Term) antibody
Verified ARG1 适用: 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (C-Term) antibody
Verified ARG1 适用: 人, 大鼠, 小鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (AA 11-97) antibody
ARG1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ARG1-1125 unconjugated

anti-Arginase, Liver (ARG1) (C-Term) antibody
ARG1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (N-Term) antibody
ARG1 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, Pig, 马, 山羊, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (AA 293-322) antibody
ARG1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (AA 151-220) antibody
ARG1 适用: 人, 大鼠 ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (AA 1-322) antibody
ARG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (N-Term) antibody
ARG1 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, Pig, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Arginase, Liver (ARG1) (AA 300-400) antibody
ARG1 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-511R unconjugated Recombinant Antibody

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:1000. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: HepG2
Validation: KO/KD, Orthogonal

限制

仅限研究用
状态

Liquid

浓度

0.26 mg/mL

缓冲液

1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Scherwitzl, Opp, Hurtado, Pampeno, Loomis, Kannan, Yu, Meruelo: "Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors." in: Molecular therapy oncolytics, Vol. 17, pp. 431-447, (2020) (PubMed).

Glass, Masjedi, Dudzinski, Wilson, Duvall, Yull, Giorgio: "Optimizing Mannose "Click" Conjugation to Polymeric Nanoparticles for Targeted siRNA Delivery to Human and Murine Macrophages." in: ACS omega, Vol. 4, Issue 16, pp. 16756-16767, (2019) (PubMed).

Gomez, Baylis, Durgin, Newman, Alencar, Mahan, St Hilaire, Müller, Waisman, Francis, Pinteaux, Randolph, Gram, Owens: "Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice." in: Nature medicine, Vol. 24, Issue 9, pp. 1418-1429, (2019) (PubMed).

Zhang, Tang, Huang, Zhou, Cui, Weng, Liu, Kim, Lee, Perez-Neut, Ding, Czyz, Hu, Ye, He, Zheng, Shuman, Dai, Ren, Roeder, Becker, Zhao: "Metabolic regulation of gene expression by histone lactylation." in: Nature, Vol. 574, Issue 7779, pp. 575-580, (2019) (PubMed).

Shen, Li, Ma, Tian, Hong, Zhai, Li, Huang, Shi: "IRAK-M alters the polarity of macrophages to facilitate the survival of Mycobacterium tuberculosis." in: BMC microbiology, Vol. 17, Issue 1, pp. 185, (2018) (PubMed).

Zhu, Zhang, Lu, Gao, Cai, Sui, Su, Shen, Xie: "Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy." in: International journal of molecular medicine, Vol. 40, Issue 2, pp. 281-292, (2018) (PubMed).

Wu, Sun, Li, Shen, Zhai, Yu, Chen et al.: "Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory ..." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 36, (2018) (PubMed).

Romano, Parrinello, Vetro, Tibullo, Giallongo, La Cava, Chiarenza, Motta, Caruso, Villari, Tripodo, Cosentino, Ippolito, Consoli, Gallamini, Pileri, Di Raimondo: "The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma." in: Oncotarget, Vol. 7, Issue 41, pp. 67333-67346, (2018) (PubMed).

Carmona-Fontaine, Deforet, Akkari, Thompson, Joyce, Xavier: "Metabolic origins of spatial organization in the tumor microenvironment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 11, pp. 2934-2939, (2017) (PubMed).

Beachley, Wolf, Sadtler, Manda, Jacobs, Blatchley, Bader, Pandey, Pardoll, Elisseeff: "Tissue matrix arrays for high-throughput screening and systems analysis of cell function." in: Nature methods, Vol. 12, Issue 12, pp. 1197-204, (2016) (PubMed).

Harmon, Fronhofer, Keller, Feustel, Zhu, Xu, Avram, Jones, Nagarajan, Lennartz: "Anti-Inflammatory Immune Skewing Is Atheroprotective: Apoe-/-Fc?RIIb-/- Mice Develop Fibrous Carotid Plaques." in: Journal of the American Heart Association, Vol. 3, Issue 6, (2014) (PubMed).
抗原

Liver Arginase (ARG1) (Arginase, Liver (ARG1))

别名

arginase 1

背景

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.

Cellular Localization: Cytoplasm

分子量

35 kDa

基因ID

383

UniProt

P05089

途径

Cellular Response to Molecule of Bacterial Origin