TEAD4 抗体 (Center)
Quick Overview for TEAD4 抗体 (Center) (ABIN2856634)
抗原
See all TEAD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 小鼠, 猪
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交叉反应 (详细)
- Mouse (91 %), Pig (94 %)
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产品特性
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Rabbit Polyclonal antibody to TEAD4 (TEA domain family member 4)
TEAD4 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human TEAD4. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: HepG2 necleus
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma." in: Cancer cell international, Vol. 18, pp. 178, (2018) (PubMed).
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: "TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma." in: Cancer cell international, Vol. 18, pp. 178, (2018) (PubMed).
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- TEAD4 (TEA Domain Family Member 4 (TEAD4))
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别名
- TEAD4
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背景
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This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
Cellular Localization: Nucleus -
分子量
- 48 kDa
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基因ID
- 7004
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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