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PCBP2 抗体 (C-Term)

PCBP2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856597
发货至: 中国
  • 抗原 See all PCBP2 抗体
    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
    抗原表位
    • 5
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    C-Term
    适用
    • 34
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    • 6
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    • 4
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    • 2
    • 2
    • 1
    • 1
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    宿主
    • 31
    • 4
    克隆类型
    • 29
    • 6
    多克隆
    标记
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
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    This PCBP2 antibody is un-conjugated
    应用范围
    • 23
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    • 4
    • 4
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to PCBP2 (poly(rC) binding protein 2)
    PCBP2 antibody [C2C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PCBP2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PCBP2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HepG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
    别名
    poly(rC) binding protein 2 (PCBP2 产品)
    别名
    HNRNPE2 antibody, HNRPE2 antibody, hnRNP-E2 antibody, AW412548 antibody, Hnrpx antibody, alphaCP-2 antibody, PCBP3 antibody, fb36h02 antibody, wu:fb36h02 antibody, zgc:55964 antibody, PCBP2 antibody, poly(rC) binding protein 2 antibody, poly(rC) binding protein 2 L homeolog antibody, PCBP2 antibody, Pcbp2 antibody, pcbp2 antibody, pcbp2.L antibody
    背景
    The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Nucleus , Cytoplasm
    分子量
    39 kDa
    基因ID
    5094
    UniProt
    Q15366
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