PCBP2 抗体 (C-Term)
Quick Overview for PCBP2 抗体 (C-Term) (ABIN2856597)
抗原
See all PCBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to PCBP2 (poly(rC) binding protein 2)
PCBP2 antibody [C2C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PCBP2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Poly(rC) Binding Protein 2 (PCBP2) antibody
PCBP2 适用: 人 WB, IF, ICC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-362) antibodyPCBP2 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-130) antibodyPCBP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-362) antibodyPCBP2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6B6 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-362) antibodyPCBP2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (Middle Region) antibodyPCBP2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 171-293) antibodyPCBP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-363) antibodyPCBP2 适用: 人 WB, ELISA, IHC, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) antibodyPCBP2 适用: 人, 小鼠, 斑马鱼 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (Internal Region) antibodyPCBP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
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别名
- poly(rC) binding protein 2
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背景
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The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Nucleus , Cytoplasm -
分子量
- 39 kDa
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基因ID
- 5094
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UniProt
- Q15366
抗原
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