HRH2 抗体 (N-Term)
(2 references)Quick Overview for HRH2 抗体 (N-Term) (ABIN2856570)
抗原
See all HRH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人, 大鼠
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产品特性
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Rabbit Polyclonal antibody to Histamine H2 Receptor (histamine receptor H2)
Histamine H2 Receptor antibody [N1], N-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histamine H2 Receptor. The exact sequence is proprietary.
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亚型
- IgG
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anti-Histamine Receptor H2 (HRH2) (C-Term) antibody
Verified HRH2 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (AA 161-259) antibodyHRH2 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (Cytoplasmic Domain) antibodyHRH2 适用: 人, 猴 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (AA 309-323) antibodyVerified HRH2 适用: 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (AA 161-173), (Extracellular) antibodyHRH2 适用: 大鼠 WB, IF, IHC, IC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (Extracellular Domain) antibodyHRH2 适用: 人, 大鼠 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (Internal Region) antibodyHRH2 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (AA 150-250) antibodyHRH2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (Center) antibodyHRH2 适用: 人, 大鼠, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: NT2D1 , PC-3 , U87-MG , SK-N-SH
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.75 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." in: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).
: "Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics." in: Microcirculation (New York, N.Y. : 1994), Vol. 21, Issue 7, pp. 593-605, (2015) (PubMed).
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: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." in: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).
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- HRH2 (Histamine Receptor H2 (HRH2))
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别名
- histamine receptor H2
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背景
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Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Cell membrane, Multi-pass membrane protein -
分子量
- 40 kDa
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基因ID
- 3274
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UniProt
- P25021
抗原
-
