UNC13D 抗体 (C-Term)
Quick Overview for UNC13D 抗体 (C-Term) (ABIN2856569)
抗原
See all UNC13D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to Munc 13-4 (unc-13 homolog D (C. elegans))
Munc 13-4 antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Munc 13-4. The exact sequence is proprietary.
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亚型
- IgG
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anti-Unc-13 Homolog D (UNC13D) (AA 2-100) antibody
UNC13D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Unc-13 Homolog D (UNC13D) (Internal Region) antibodyVerified UNC13D 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 7-172) antibodyUNC13D 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyVerified UNC13D 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) antibodyUNC13D 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 1-1090) antibodyUNC13D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (C-Term) antibodyUNC13D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Unc-13 Homolog D (UNC13D) (AA 891-1090) antibodyUNC13D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat , K562
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- UNC13D (Unc-13 Homolog D (UNC13D))
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别名
- unc-13 homolog D
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背景
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This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Cellular Localization: Cytoplasm , Membrane, Peripheral membrane protein -
分子量
- 123 kDa
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基因ID
- 201294
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UniProt
- Q70J99
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
-
