PDGFRB 抗体
Our Local Distributor
北京 101111
Quick Overview for PDGFRB 抗体 (ABIN285643)
抗原
See all PDGFRB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody reacts with bovine albumin by immunoelectrophoresis and ELISA,and may also cross-react with albumin from other species.1 ml@ 1 mg/ml
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- PDGFr antibody was raised in sheep using PDGFr-rDNA expression of the b domain (GST fusion) as the immunogen.
-
-
-
-
应用备注
- Optimal conditions should be determined byt he investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- Lot specific
-
缓冲液
- Purified by protein G chromatography and supplied in PBS with 0.05 % NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
-
-
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
-
别名
- PDGFr
-
背景
- Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
-