CHMP5 抗体
Quick Overview for CHMP5 抗体 (ABIN2856420)
抗原
See all CHMP5 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to CHMP5 (chromatin modifying protein 5)
CHMP5 antibody [N1C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CHMP5. The exact sequence is proprietary.
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亚型
- IgG
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anti-Charged Multivesicular Body Protein 5 (CHMP5) (AA 1-219) antibody
CHMP5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 5 (CHMP5) (C-Term) antibodyVerified CHMP5 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2
Validation: Comparison, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.7 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
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别名
- charged multivesicular body protein 5
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背景
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CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]
Cellular Localization: Cytoplasm , cytosol , Endosome membrane, Peripheral membrane protein , Cytoplasm , cytosol , Endosome membrane -
分子量
- 25 kDa
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基因ID
- 51510
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UniProt
- Q9NZZ3
抗原
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