IPO7 抗体 (C-Term)
Quick Overview for IPO7 抗体 (C-Term) (ABIN2856366)
抗原
See all IPO7 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- C-Term
-
特异性
- Knockdown/Knockout validation was supported by references (PMID:25999477)
-
交叉反应
- 人
-
产品特性
-
Rabbit Polyclonal antibody to Importin 7 (importin 7)
Importin 7 antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Importin 7. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Importin 7 (IPO7) (AA 950-1038) antibody
IPO7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Importin 7 (IPO7) antibodyIPO7 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Importin 7 (IPO7) (AA 142-169), (N-Term) antibodyIPO7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB26876 unconjugated
anti-Importin 7 (IPO7) (AA 1-50) antibodyIPO7 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: Jurkat
Validation: KO/KD
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- IPO7 (Importin 7 (IPO7))
-
别名
- importin 7
-
背景
-
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
Cellular Localization: Cytoplasm , Nucleus -
分子量
- 120 kDa
-
基因ID
- 10527
-
UniProt
- O95373
-
途径
- Protein targeting to Nucleus
抗原
-
