DBNL 抗体 (N-Term)
Quick Overview for DBNL 抗体 (N-Term) (ABIN2856301)
抗原
See all DBNL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 小鼠, 大鼠, 牛
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交叉反应 （详细）
- Mouse (92 %), Rat (92 %), Bovine (84 %)
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产品特性
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Rabbit Polyclonal antibody to HIP55 (drebrin-like)
HIP55 antibody [N1], N-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HIP55. The exact sequence is proprietary.
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亚型
- IgG
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anti-Drebrin-Like (DBNL) (N-Term) antibody
Verified DBNL 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Drebrin-Like (DBNL) (AA 201-300) antibodyDBNL 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Drebrin-Like (DBNL) (AA 251-300) antibodyDBNL 适用: 人, 小鼠, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Drebrin-Like (DBNL) (AA 131-430) antibodyDBNL 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: HeLaS3 , Molt-4
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DBNL (Drebrin-Like (DBNL))
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别名
- HIP55
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背景
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Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
Cellular Localization: Cytoplasm , cytoskeleton , Cell projection , lamellipodium -
分子量
- 48 kDa
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基因ID
- 28988
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途径
- TCR Signaling, Regulation of Actin Filament Polymerization
抗原
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