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CD2AP 抗体

This anti-CD2AP antibody is a 兔 多克隆 antibody detecting CD2AP in WB, ICC, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN2856284
发货至: 中国

Quick Overview for CD2AP 抗体 (ABIN2856284)

抗原

See all CD2AP (Cd2ap) 抗体
CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

适用

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宿主

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克隆类型

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多克隆

标记

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This CD2AP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit Polyclonal antibody to CD2AP (CD2-associated protein)
    CD2AP antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human CD2AP. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A375 , Rat2 , A431 , HeLa , HepG2 , K562 , THP-1 , HL-60

    Validation: Comparison, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.17 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

    别名

    CD2 associated protein

    背景

    This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

    Cellular Localization: Cytoplasm , cytoskeleton , Cell projection , ruffle

    分子量

    71 kDa

    基因ID

    23607

    UniProt

    Q9Y5K6
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