DPM1 抗体 (Center)
Quick Overview for DPM1 抗体 (Center) (ABIN2856272)
抗原
See all DPM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 小鼠, 牛, 猪, 大鼠, 非洲爪蟾
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交叉反应 (详细)
- Mouse (90 %), Bovine (92 %), Pig (93 %), Rat (91 %), Xenopus laevis (86 %)
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产品特性
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Rabbit Polyclonal antibody to DPM1 (dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit)
DPM1 antibody [N1C2] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human DPM1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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说明
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Positive Control: NT2D1 , U87-MG , MCF-7
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.95 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))
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别名
- DPM1
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背景
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Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
Cellular Localization: Endoplasmic reticulum -
分子量
- 30 kDa
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基因ID
- 8813
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途径
- Inositol Metabolic Process
抗原
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