LAMa4 抗体 (C-Term)
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北京 101111
Quick Overview for LAMa4 抗体 (C-Term) (ABIN2856262)
抗原
See all LAMa4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 小鼠
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产品特性
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Rabbit Polyclonal antibody to Laminin alpha 4 (laminin, alpha 4)
Laminin alpha 4 antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human Laminin alpha 4. The exact sequence is proprietary.
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亚型
- IgG
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anti-Laminin, alpha 4 (LAMa4) (AA 457-630) antibody
LAMa4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, alpha 4 (LAMa4) (AA 745-940) antibodyLAMa4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, alpha 4 (LAMa4) (AA 1593-1823) antibodyLAMa4 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, alpha 4 (LAMa4) (Internal Region) antibodyLAMa4 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, alpha 4 (LAMa4) (AA 1-120) antibodyLAMa4 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Laminin, alpha 4 (LAMa4) (Center) antibodyLAMa4 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, alpha 4 (LAMa4) (AA 481-530) antibodyLAMa4 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, alpha 4 (LAMa4) (AA 102-234) antibodyLAMa4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, alpha 4 (LAMa4) (AA 1-100) antibodyLAMa4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Laminin, alpha 4 (LAMa4) (AA 1474-1508), (C-Term) antibodyLAMa4 适用: 人 WB 宿主: 兔 Polyclonal RB52641 unconjugated
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应用备注
- IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.74 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- LAMa4 (Laminin, alpha 4 (LAMa4))
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别名
- laminin subunit alpha 4
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背景
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Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known. Tissue-specific utilization of alternative polyA-signal has been described in literature. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Cellular Localization: Secreted , extracellular space , extracellular matrix , basement membrane -
分子量
- 203 kDa
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基因ID
- 3910
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UniProt
- Q16363
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途径
- Brown Fat Cell Differentiation
抗原
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