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Factor XI 抗体

This anti-Factor XI antibody is a 兔 多克隆 antibody detecting Factor XI in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2856233
发货至: 中国

Quick Overview for Factor XI 抗体 (ABIN2856233)

抗原

See all Factor XI (F11) 抗体
Factor XI (F11) (Coagulation Factor XI (F11))

适用

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宿主

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克隆类型

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多克隆

标记

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This Factor XI antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    产品特性

    Rabbit Polyclonal antibody to Factor XI (coagulation factor XI)
    Factor XI antibody [N1N3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Factor XI. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.85 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Factor XI (F11) (Coagulation Factor XI (F11))

    别名

    coagulation factor XI

    背景

    This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

    Cellular Localization: Secreted

    分子量

    70 kDa

    基因ID

    2160

    UniProt

    P03951
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