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FOLR2 抗体

This anti-FOLR2 antibody is a 兔 多克隆 antibody detecting FOLR2 in WB, IHC, IHC (p), IF 和 ICC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2856196
发货至: 中国

Quick Overview for FOLR2 抗体 (ABIN2856196)

抗原

See all FOLR2 抗体
FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

适用

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宿主

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克隆类型

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多克隆

标记

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This FOLR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to Folate receptor beta (folate receptor 2 (fetal))
    Folate receptor beta antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Folate Receptor beta. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.2 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Meredith, MacNeil, Trasler, Baltz: "Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size." in: Biology of reproduction, Vol. 94, Issue 6, pp. 125, (2017) (PubMed).

  • 抗原

    FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

    别名

    folate receptor beta

    背景

    The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

    Cellular Localization: Cell membrane, Lipid-anchor , GPI-anchor , Secreted

    分子量

    29 kDa

    基因ID

    2350

    UniProt

    P14207

    途径

    Dicarboxylic Acid Transport
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