OPTN 抗体
Quick Overview for OPTN 抗体 (ABIN2856108)
抗原
See all OPTN 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to Optineurin (optineurin)
Optineurin antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Optineurin. The exact sequence is proprietary.
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亚型
- IgG
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anti-Optineurin (OPTN) (AA 341-440) antibody
OPTN 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-300) antibodyOPTN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-577) antibodyOPTN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-577) antibodyOPTN 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 575-591) antibodyOPTN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-577) antibodyOPTN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 559-575) antibodyOPTN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 72-121) antibodyOPTN 适用: 人, 小鼠, 犬, 豚鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (C-Term) antibodyOPTN 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (N-Term) antibodyOPTN 适用: 人, 犬, Cow, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , H1299 , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- OPTN (Optineurin (OPTN))
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别名
- optineurin
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背景
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This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
Cellular Localization: Cytoplasm , perinuclear region , Golgi apparatus -
分子量
- 66 kDa
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基因ID
- 10133
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UniProt
- Q96CV9
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途径
- M Phase
抗原
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