AXIN2 抗体
Quick Overview for AXIN2 抗体 (ABIN2856107)
抗原
See all AXIN2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit polyclonal antibody to axin 2 (axin 2 (conductin, axil))
axin 2 antibody [N2C2], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Axin 2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Axin 2 (AXIN2) (AA 650-750) antibody
AXIN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 816-843) antibodyAXIN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 56-73) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) antibodyAXIN2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 331-430) antibodyAXIN2 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 350-631) antibodyAXIN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 11-77) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 611-710) antibodyAXIN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Axin 2 (AXIN2) (N-Term) antibodyAXIN2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 816-843), (C-Term) antibodyAXIN2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26798 unconjugated
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应用备注
- IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- AXIN2 (Axin 2 (AXIN2))
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别名
- axin 2
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背景
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The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
Cellular Localization: Cytoplasm -
分子量
- 94 kDa
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基因ID
- 8313
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UniProt
- Q9Y2T1
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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