OTC 抗体
Quick Overview for OTC 抗体 (ABIN2856045)
抗原
See all OTC 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to OTC (ornithine carbamoyltransferase)
OTC antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human OTC. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:30000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Mouse liver,Human liver
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.39 mg/mL
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缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- OTC (Ornithine Carbamoyltransferase (OTC))
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别名
- ornithine carbamoyltransferase
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背景
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This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Cellular Localization: Mitochondrion matrix -
分子量
- 40 kDa
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基因ID
- 5009
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UniProt
- P00480
抗原
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