POLRMT 抗体 (Center)
(3 references)-
- 抗原 See all POLRMT 抗体
- POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))
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抗原表位
- Center
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLRMT antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Cleavage Under Targets and Release Using Nuclease (CUT&RUN)
- 产品特性
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Rabbit Polyclonal antibody to mtRNA polymerase (polymerase (RNA) mitochondrial (DNA directed))
mtRNA polymerase antibody [N2N3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human mtRNA polymerase. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product POLRMT Primary Antibody
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anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 42-230) antibody
POLRMT 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 1121-1230) antibodyPOLRMT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 1121-1230) antibodyPOLRMT 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 1-100) antibodyPOLRMT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H7 unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 282-405) antibodyPOLRMT 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 1-1230) antibodyPOLRMT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- 说明
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Positive Control: HepG2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.31 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Non-B-Form DNA Is Enriched at Centromeres." in: Molecular biology and evolution, Vol. 35, Issue 4, pp. 949-962, (2019) (PubMed).
: "Unexpected conformational variations of the human centromeric chromatin complex." in: Genes & development, Vol. 32, Issue 1, pp. 20-25, (2018) (PubMed).
: "Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I." in: Nucleic acids research, Vol. 41, Issue 21, pp. 9848-57, (2014) (PubMed).
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: "Non-B-Form DNA Is Enriched at Centromeres." in: Molecular biology and evolution, Vol. 35, Issue 4, pp. 949-962, (2019) (PubMed).
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- 抗原
- POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))
- 别名
- MtRNA Polymerase (POLRMT 产品)
- 别名
- polrmt-a antibody, mtRPO antibody, wu:fb73g10 antibody, si:dkeyp-74c5.5 antibody, POLRMT antibody, APOLMT antibody, MTRNAP antibody, MTRPOL antibody, h-mtRPOL antibody, 1110018N15Rik antibody, 4932416K13 antibody, RNA polymerase mitochondrial antibody, polymerase (RNA) mitochondrial (DNA directed) L homeolog antibody, polymerase (RNA) mitochondrial (DNA directed) antibody, Polrmt antibody, polrmt.L antibody, polrmt antibody, POLRMT antibody
- 背景
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This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.
Cellular Localization: Mitochondrion - 分子量
- 139 kDa
- 基因ID
- 5442
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