POLRMT 抗体 (Center)
(3 references)Quick Overview for POLRMT 抗体 (Center) (ABIN2856044)
抗原
See all POLRMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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产品特性
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Rabbit Polyclonal antibody to mtRNA polymerase (polymerase (RNA) mitochondrial (DNA directed))
mtRNA polymerase antibody [N2N3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human mtRNA polymerase. The exact sequence is proprietary.
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亚型
- IgG
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anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 42-230) antibody
POLRMT 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 1121-1230) antibodyPOLRMT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 1121-1230) antibodyPOLRMT 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 1-100) antibodyPOLRMT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H7 unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 282-405) antibodyPOLRMT 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (AA 1-1230) antibodyPOLRMT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.31 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Non-B-Form DNA Is Enriched at Centromeres." in: Molecular biology and evolution, Vol. 35, Issue 4, pp. 949-962, (2019) (PubMed).
: "Unexpected conformational variations of the human centromeric chromatin complex." in: Genes & development, Vol. 32, Issue 1, pp. 20-25, (2018) (PubMed).
: "Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I." in: Nucleic acids research, Vol. 41, Issue 21, pp. 9848-57, (2014) (PubMed).
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: "Non-B-Form DNA Is Enriched at Centromeres." in: Molecular biology and evolution, Vol. 35, Issue 4, pp. 949-962, (2019) (PubMed).
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- POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))
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别名
- MtRNA Polymerase
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背景
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This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.
Cellular Localization: Mitochondrion -
分子量
- 139 kDa
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基因ID
- 5442
抗原
-
