BPNT1 抗体
Quick Overview for BPNT1 抗体 (ABIN2856006)
抗原
See all BPNT1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1)
BPNT1 antibody [N1C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.
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亚型
- IgG
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anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 1-100) antibody
BPNT1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2E1 unconjugated
anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (C-Term) antibodyVerified BPNT1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 1-261) antibodyBPNT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 35-84) antibodyBPNT1 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 7-308) antibodyBPNT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Mouse liver , HeLaS3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.7 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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别名
- 3'(2'), 5'-bisphosphate nucleotidase 1
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背景
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BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
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分子量
- 33 kDa
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基因ID
- 10380
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UniProt
- O95861
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途径
- Inositol Metabolic Process
抗原
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