Proteasome 20S alpha 4 (Center) 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in ICC, IF 和 WB. Suitable for 人.
Quick Overview for Proteasome 20S alpha 4 (Center) 抗体 (ABIN2855988)
抗原
Proteasome 20S alpha 4
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
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抗原表位
- Center
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交叉反应
- 猪, 猕猴, 牛
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交叉反应 （详细）
- Pig (100 %), Rhesus Monkey (100 %), Bovine (100 %)
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产品特性
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Rabbit Polyclonal antibody to Proteasome 20S alpha 4 (proteasome (prosome, macropain) subunit, alpha type, 4)
Proteasome 20S alpha 4 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Proteasome 20S alpha 4. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: HeLa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Proteasome 20S alpha 4
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背景
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Cytoplasm , Nucleus -
分子量
- 29 kDa
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基因ID
- 5685
抗原
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