SPHK1 抗体 (C-Term)
Quick Overview for SPHK1 抗体 (C-Term) (ABIN2855922)
抗原
See all SPHK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
交叉反应
- 人
-
产品特性
-
Rabbit Polyclonal antibody to SPHK1 (sphingosine kinase 1)
SPHK1 antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SPHK1. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibody
SPHK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03621 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 313-343) antibodySPHK1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 148-398) antibodySPHK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibodySPHK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 50-384) antibodySPHK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30), (N-Term) antibodySPHK1 适用: 人 WB 宿主: 兔 Polyclonal RB3619 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 59-89) antibodySPHK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30) antibodySPHK1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: Molt-4
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.17 mg/mL
-
缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
-
别名
- sphingosine kinase 1
-
背景
-
Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM]
-
分子量
- 43 kDa
-
基因ID
- 8877
-
UniProt
- Q9NYA1
-
途径
- VEGF Signaling
抗原
-
