FUBP1 抗体
Quick Overview for FUBP1 抗体 (ABIN2855856)
抗原
See all FUBP1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to FUBP1 (far upstream element-binding protein 1)
FUBP1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human FUBP1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: mouse brain , rat brain
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.92 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons." in: Nucleic acids research, Vol. 45, Issue 1, pp. 417-434, (2017) (PubMed).
: "Exon-centric regulation of ATM expression is population-dependent and amenable to antisense modification by pseudoexon targeting." in: Scientific reports, Vol. 6, pp. 18741, (2016) (PubMed).
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Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons." in: Nucleic acids research, Vol. 45, Issue 1, pp. 417-434, (2017) (PubMed).
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- FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))
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别名
- far upstream element binding protein 1
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背景
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This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.
Cellular Localization: Nucleus -
分子量
- 68 kDa
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基因ID
- 8880
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UniProt
- Q96AE4
抗原
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